Pub. Date : 2021 Apr
PMID : 33073679
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | The purpose of this study was to investigate the effect of therapeutic inhibition of mTOR (mechanistic target of rapamycin) on resistance of CSCs to cisplatin, a prototypic platinum-based chemotherapeutic agent. | Platinum | mechanistic target of rapamycin kinase | Homo sapiens | ||
2 | The purpose of this study was to investigate the effect of therapeutic inhibition of mTOR (mechanistic target of rapamycin) on resistance of CSCs to cisplatin, a prototypic platinum-based chemotherapeutic agent. | Platinum | mechanistic target of rapamycin kinase | Homo sapiens | ||
3 | Collectively, these results demonstrate that therapeutic inhibition of mTOR ablates cytotoxic-resistant CSCs, and they suggest that a combination of an mTOR inhibitor and platinum-based chemotherapy might be beneficial to patients with salivary gland mucoepidermoid carcinoma. | Platinum | mechanistic target of rapamycin kinase | Homo sapiens |