Pub. Date : 2021 Feb
PMID : 33070276
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The c-Myc expression and the progression of cell division cycle were restored upon the addition of mevalonate to the culture media containing statins. | Mevalonic Acid | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | Together, these data demonstrate that statins inhibit the mevalonate pathway which is tightly coupled to oxidative branch of the pentose phosphate pathway, c-Myc expression, cell division cycle progression, and cellular senescence. | Mevalonic Acid | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |