Title : CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage.

Pub. Date : 2020 Oct 13

PMID : 33066270






1 Functional Relationships(s)
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1 Artificial senescence induced by H2O2 caused a dose-dependent increase in Ccn3 gene and CCN3 protein expression, along with enhanced expression of p21 and p53 mRNA and proteins, as well as SA-beta gal activity. Hydrogen Peroxide KRAS proto-oncogene, GTPase Rattus norvegicus