Title : Effect directed synthesis of a new tyrosinase inhibitor with anti-browning activity.

Pub. Date : 2021 Mar 30

PMID : 33039744






1 Functional Relationships(s)
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1 The objective of this work is to describe a novel platform for the discovery of tyrosinase inhibitors, based on (a) one-pot preparation of a library of thiosemicarbazide compounds, (b) biological evaluation using tyrosinase TLC bioautography, (c) inhibitor identification via mass spectrometry coupled to bioautography. thiosemicarbazide tyrosinase Homo sapiens