Title : A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models.

Pub. Date : 2021 Jan

PMID : 33036015






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1 The data demonstrate for the first time that a CB1R allosteric modulator ameliorates the behavioral deficits in two model of increased dopamine, warranting further investigation as a potential therapeutic target in psychiatry. Dopamine cannabinoid receptor 1 (brain) Mus musculus