| Protein Name | cannabinoid receptor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12801 |
| Gene Symbol | Cnr1 |
| UniProt | P47746 (CNR1_MOUSE), A0A385KNU8 (A0A385KNU8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
677
Total Number of Articles : 1402 |
Description |
cannabinoid receptor 1 |
| Gene Summary |
Enables cannabinoid receptor activity. Involved in regulation of presynaptic cytosolic calcium ion concentration and retrograde trans-synaptic signaling by endocannabinoid. Acts upstream of or within axonal fasciculation and glucose homeostasis. Located in growth cone. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and presynaptic membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in heroin dependence; obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |