Title : 3-Deazaadenosine, an S-adenosylhomocysteine hydrolase inhibitor, attenuates lipopolysaccharide-induced inflammatory responses via inhibition of AP-1 and NF-κB signaling.

Pub. Date : 2020 Dec

PMID : 33035507






1 Functional Relationships(s)
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1 It also reduced mRNA expression of inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-alpha, interleukin-1beta (IL-1 beta), and IL-6, indicating that 3-DA has anti-inflammatory properties in murine and human macrophages. 3-da prostaglandin-endoperoxide synthase 2 Mus musculus