Title : 3-Deazaadenosine, an S-adenosylhomocysteine hydrolase inhibitor, attenuates lipopolysaccharide-induced inflammatory responses via inhibition of AP-1 and NF-κB signaling.

Pub. Date : 2020 Dec

PMID : 33035507






1 Functional Relationships(s)
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1 Moreover, 3-DA strongly blocked AP-1 and NF-kappaB luciferase activity under PMA-, MyD88-, and TRIF-stimulated conditions and decreased the translocation of c-Jun, c-Fos, p65, and p50 into the nucleus. 3-da RELA proto-oncogene, NF-kB subunit Homo sapiens