Title : Involvement of clock gene expression, bone morphogenetic protein and activin in adrenocortical steroidogenesis by human H295R cells.

Pub. Date : 2021 Feb 28

PMID : 33028758






3 Functional Relationships(s)
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1 After FSK induction, mRNA levels of StAR and CYP11B2 were highest at 12 hours and CYP17 mRNA level reached a peak at 6 hours, but HSD3B1 mRNA level was transiently decreased at 3 hours. Colforsin cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Knockdown of Clock gene by siRNA led to a significant reduction of FSK-induced expression of StAR and CYP17 after 12-h treatment with FSK. Colforsin cytochrome P450 family 17 subfamily A member 1 Homo sapiens
3 Knockdown of Clock gene by siRNA led to a significant reduction of FSK-induced expression of StAR and CYP17 after 12-h treatment with FSK. Colforsin cytochrome P450 family 17 subfamily A member 1 Homo sapiens