Title : Berberine affects mitochondrial activity and cell growth of leukemic cells from chronic lymphocytic leukemia patients.

Pub. Date : 2020 Oct 5

PMID : 33020573






1 Functional Relationships(s)
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1 Interestingly, BRB lowered the apoptotic threshold of ABT-199/Venetoclax, a promising BH3-mimetic whose cytotoxic activity is counteracted by high Mcl-1/Bcl-xL expression and increased mitochondrial oxidative phosphorylation. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid MCL1 apoptosis regulator, BCL2 family member Homo sapiens