Title : Xanthohumol Effect on 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Japanese Quails in Terms of Serum Lipids, Liver Enzymes, Estradiol, and Thyroid Hormones.

Pub. Date : 2020 Sep 29

PMID : 33015460






3 Functional Relationships(s)
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1 TCDD is considered a carcinogen and has proinflammatory influence on animals and humans, promoting free radicals" formation, and binding with the aryl hydrocarbon receptor (AhR) leads to expression of cytochrome p-450 genes that in turn predisposes to mutations. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor Homo sapiens
2 TCDD is considered a carcinogen and has proinflammatory influence on animals and humans, promoting free radicals" formation, and binding with the aryl hydrocarbon receptor (AhR) leads to expression of cytochrome p-450 genes that in turn predisposes to mutations. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor Homo sapiens
3 Natural flavonoids, in this case xanthohumol (XN), have been reported to attenuate TCDD toxicity through inhibition of the transformation of the AhR. Polychlorinated Dibenzodioxins aryl hydrocarbon receptor Homo sapiens