Pub. Date : 2020 Nov
PMID : 33005243
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Irbesartan ameliorates myocardial fibrosis in diabetic cardiomyopathy rats by inhibiting the TGFbeta1/Smad2/3 pathway. | Irbesartan | transforming growth factor, beta 1 | Rattus norvegicus |
| 2 | Changes in the aforementioned indicators were reversed after treatment with irbesartan, where the protein expression levels of TGFbeta1 and p-Smad2/3 in myocardial tissue were also significantly reduced. | Irbesartan | transforming growth factor, beta 1 | Rattus norvegicus |
| 3 | Therefore, the present results demonstrated that irbesartan reduced the activity of the TGFbeta1/Smad2/3 pathway and ameliorated diabetic MF by downregulating the expression of TGFbeta1. | Irbesartan | transforming growth factor, beta 1 | Rattus norvegicus |
| 4 | Therefore, the present results demonstrated that irbesartan reduced the activity of the TGFbeta1/Smad2/3 pathway and ameliorated diabetic MF by downregulating the expression of TGFbeta1. | Irbesartan | transforming growth factor, beta 1 | Rattus norvegicus |