Title : Targeting Corticotroph HDAC and PI3-Kinase in Cushing Disease.

Pub. Date : 2021 Jan 1

PMID : 33000123






1 Functional Relationships(s)
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1 We also demonstrated that CUDC-907 acts through HDAC1/2 inhibition at the POMC transcriptional level combined with its PI3K-mediated inhibition of corticotroph cell viability to reduce ACTH secretion. CUDC-907 pro-opiomelanocortin-alpha Mus musculus