Pub. Date : 2020 Oct 20
PMID : 32988199
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we focus on the highly amyloidogenic H-fragment of insulin comprising the disulfide-bonded N-terminal parts of both chains. | Disulfides | insulin | Homo sapiens |
| 2 | Our study suggests that the N-terminal part of insulin"s A-chain containing the intact Cys6-Cys11 intrachain disulfide bond may constitute insulin"s major amyloid stretch which, through its bent conformation, enforces a parallel in-register alignment of beta-strands. | Disulfides | insulin | Homo sapiens |
| 3 | Our study suggests that the N-terminal part of insulin"s A-chain containing the intact Cys6-Cys11 intrachain disulfide bond may constitute insulin"s major amyloid stretch which, through its bent conformation, enforces a parallel in-register alignment of beta-strands. | Disulfides | insulin | Homo sapiens |