Title : The bromodomain and extra-terminal domain inhibitor JQ1 synergistically sensitizes human colorectal cancer cells to topoisomerase I inhibitors through repression of Mre11-mediated DNA repair pathway.

Pub. Date : 2021 Apr

PMID : 32981006






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Camptothecin (CPT) and its derivatives, irinotecan and topotecan are specific topoisomerase I (Top1) inhibitors and potent anticancer drugs. Camptothecin DNA topoisomerase I Homo sapiens
2 Camptothecin (CPT) and its derivatives, irinotecan and topotecan are specific topoisomerase I (Top1) inhibitors and potent anticancer drugs. Camptothecin DNA topoisomerase I Homo sapiens