Title : Pyrroloquinoline Quinone Inhibits Rotenone-Induced Microglia Inflammation by Enhancing Autophagy.

Pub. Date : 2020 Sep 23

PMID : 32977419






1 Functional Relationships(s)
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1 In rotenone-treated BV2 cells, PQQ dose-dependently decreased lactate dehydrogenase (LDH) release and suppressed the up-regulation of pro-inflammation factors, such as interleukin-1beta (IL-1beta), IL-6 and tumor necrosis factor-alpha (TNF-alpha) in the cultured media, as well as nitric oxide (NO) release induced by rotenone. PQQ Cofactor interleukin 1 alpha Mus musculus