Title : Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses.

Pub. Date : 2021 Feb 25

PMID : 32976550






1 Functional Relationships(s)
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1 In vitro, inducible Treg differentiation from naive CD4+ T cells was enhanced by IRX4204; in vivo, IRX4204 increased the conversion of donor Foxp3- T cells into peripheral Foxp3+ Tregs in GVHD mice. treg CD4 antigen Mus musculus