Title : Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.

Pub. Date : 2020 Dec

PMID : 32973300






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1 CONCLUSION: These results provide the most comprehensive data set of DPYD and TPMT variability published to date with important implications for population-adjusted genetic profiling strategies of fluoropyrimidine and thiopurine risk factors and precision public health. 2-mercaptopyrazine dihydropyrimidine dehydrogenase Homo sapiens