Title : Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease.

Pub. Date : 2020 Dec 1

PMID : 32964723






1 Functional Relationships(s)
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1 Since fibroblasts play a major role in the production and maintenance of extracellular matrix in emphysema, primary lung fibroblasts were treated with the ERK inhibitor LY3214996 or the c-RAF inhibitor GW5074, resulting in less S100A9-induced MMP-3, MMP-9, MCP-1, IL-6, and IL-8. 5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone chemokine (C-C motif) ligand 2 Mus musculus