Title : The G Protein-Coupled Receptor PAC1 Regulates Transactivation of the Receptor Tyrosine Kinase HER3.

Pub. Date : 2021 Aug

PMID : 32964398






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The increase in EGFR tyrosine phosphorylation caused by PACAP was blocked by the EGFR tyrosine kinase inhibitor (TKI) gefitinib, or PACAP(6-38), a PAC1 antagonist. Tyrosine adenylate cyclase activating polypeptide 1 Homo sapiens
2 The increase in HER2 tyrosine phosphorylation caused by PACAP was inhibited by trastuzumab, a monoclonal antibody (mAb) for HER2, or PACAP(6-38). Tyrosine adenylate cyclase activating polypeptide 1 Homo sapiens
3 The increase in HER2 tyrosine phosphorylation caused by PACAP was inhibited by trastuzumab, a monoclonal antibody (mAb) for HER2, or PACAP(6-38). Tyrosine adenylate cyclase activating polypeptide 1 Homo sapiens
4 The increase in HER3 tyrosine phosphorylation caused by PACAP was inhibited by HER3 mAb3481 or PACAP(6-38). Tyrosine adenylate cyclase activating polypeptide 1 Homo sapiens
5 The increase in HER3 tyrosine phosphorylation caused by PACAP was inhibited by HER3 mAb3481 or PACAP(6-38). Tyrosine adenylate cyclase activating polypeptide 1 Homo sapiens