Protein Name adenylate cyclase activating polypeptide 1
Organism Homo sapiens
Gene ID 116
Gene Symbol

ADCYAP1

UniProt P18509 (PACA_HUMAN), B7Z222 (B7Z222_HUMAN)
Relationships Total Number of functionally related compound(s) : 272
Total Number of Articles : 359
Description

adenylate cyclase activating polypeptide 1

Gene Summary

This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

synonyms
  • pituitary adenylate cyclase-activating polypeptide
  • adenylate cyclase activating polypeptide 1 (pituitary)
  • prepro-PACAP
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Properties