Title : Exosomal microRNA-23b-3p from bone marrow mesenchymal stem cells maintains T helper/Treg balance by downregulating the PI3k/Akt/NF-κB signaling pathway in intracranial aneurysm.

Pub. Date : 2020 Dec

PMID : 32956770






1 Functional Relationships(s)
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1 In addition, human BMSCs-derived exosomes inhibited the activation of the phosphatidylinositol-3 kinase (PI3K)/protein kinase B (Akt)/nuclear factor-kappa B (NF-kappaB) signaling pathway and maintained Th17/Treg balance, which in turn interfered with aneurysm formation. treg nuclear factor kappa B subunit 1 Homo sapiens