Title : Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication.

Pub. Date : 2020 Dec

PMID : 32956670






2 Functional Relationships(s)
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1 In HeLaCx43 cells treated with PMA to activate Pyk2, a decrease in Cx43 GJ intercellular communication (GJIC) was observed when assayed by dye transfer. Tetradecanoylphorbol Acetate gap junction protein, alpha 1 Rattus norvegicus
2 The ability of Pyk2 and Src inhibitors to restore Cx43 function in the presence of PMA was also observed in NRVMs. Tetradecanoylphorbol Acetate gap junction protein, alpha 1 Rattus norvegicus