Title : Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors.

Pub. Date : 2020 Dec

PMID : 32951477






4 Functional Relationships(s)
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1 It was found that benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC) inhibited yeast GR (yGR) and human GR (hGR) in a time- and concentration-dependent manner. benzyl isothiocyanate glutathione-disulfide reductase Homo sapiens
2 It was found that benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC) inhibited yeast GR (yGR) and human GR (hGR) in a time- and concentration-dependent manner. benzyl isothiocyanate glutathione-disulfide reductase Homo sapiens
3 Inhibition of intracellular GR by BITC and PEITC in cultured cancer cells was also observed. benzyl isothiocyanate glutathione-disulfide reductase Homo sapiens
4 BITC and PEITC were evaluated as competitive and irreversible inhibitors of GR. benzyl isothiocyanate glutathione-disulfide reductase Homo sapiens