Pub. Date : 2020 Sep 16
PMID : 32947765
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Coupling of HSP72 alpha-Helix Subdomains by the Unexpected Irreversible Targeting of Lysine-56 over Cysteine-17; Coevolution of Covalent Bonding. | Lysine | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 2 | The unexpected covalent inhibition of heat shock protein 72 (HSP72) by covalently targeting Lys-56 instead of Cys-17 was an interesting observation. | Lysine | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 3 | The unexpected covalent inhibition of heat shock protein 72 (HSP72) by covalently targeting Lys-56 instead of Cys-17 was an interesting observation. | Lysine | heat shock protein family A (Hsp70) member 1A | Homo sapiens |
| 4 | The closed conformation maintained the crucial salt-bridge between Glu-268 and Lys-56 residues, which strengthens the interaction affinity of the inhibitor nearly identical to adenosine triphosphate (ADP/Pi) bound to the HSP72-NBD. | Lysine | heat shock protein family A (Hsp70) member 1A | Homo sapiens |