Protein Name heat shock protein family A (Hsp70) member 1A
Organism Homo sapiens
Gene ID 3303
Gene Symbol

HSPA1A

UniProt P0DMV8 (HS71A_HUMAN), P0DMV9 (HS71B_HUMAN), A8K5I0 (A8K5I0_HUMAN), B3KTT5 (B3KTT5_HUMAN)
Relationships Total Number of functionally related compound(s) : 333
Total Number of Articles : 370
Description

heat shock protein family A (Hsp70) member 1A

Gene Summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]

synonyms
  • heat shock 70 kDa protein 1A
  • HSP70-1/HSP70-2
  • HSP70.1/HSP70.2
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Properties