Title : Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice.

Pub. Date : 2020 Nov

PMID : 32946628






2 Functional Relationships(s)
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1 BAT mitochondria from UCP3 KO mice presented a lower ability to oxidize the fatty acids and glycerol-3-phosphate, and an enhanced oxidative stress as revealed by enhanced mitochondrial electron leak, lipid hydroperoxide levels, and induction of antioxidant mitochondrial enzymatic capacity. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus
2 The absence of UCP3 also influenced the mitochondrial super-molecular protein aggregation, an important feature for fatty acid oxidation rate as well as for adequate cristae organization and mitochondrial shape. Fatty Acids uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus