| Protein Name | uncoupling protein 3 (mitochondrial, proton carrier) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22229 |
| Gene Symbol | Ucp3 |
| UniProt | P56501 (UCP3_MOUSE), B2RTM2 (B2RTM2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
123
Total Number of Articles : 131 |
Description |
uncoupling protein 3 (mitochondrial, proton carrier) |
| Gene Summary |
Enables oxidative phosphorylation uncoupler activity and proton transmembrane transporter activity. Involved in lipid hydroperoxide transport and proton transmembrane transport. Acts upstream of or within fatty acid metabolic process and response to superoxide. Located in mitochondrial inner membrane. Is expressed in adipose tissue; heart; skeletal muscle; and telencephalon. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Jul 2025] |
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