Protein Name uncoupling protein 3 (mitochondrial, proton carrier)
Organism Mus musculus
Gene ID 22229
Gene Symbol


UniProt P56501 (UCP3_MOUSE), B2RTM2 (B2RTM2_MOUSE)
Relationships Total Number of functionally related compound(s) : 123
Total Number of Articles : 131

uncoupling protein 3 (mitochondrial, proton carrier)

Gene Summary

Enables oxidative phosphorylation uncoupler activity. Acts upstream of or within fatty acid metabolic process and response to superoxide. Located in mitochondrion. Is expressed in adipose tissue; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in coronary restenosis; diabetic neuropathy; glucose metabolism disease (multiple); and obesity. Orthologous to human UCP3 (uncoupling protein 3). [provided by Alliance of Genome Resources, Apr 2022]

  • putative mitochondrial transporter UCP3
  • mitochondrial uncoupling protein 3
  • solute carrier family 25 member 9
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