Pub. Date : 2020 Oct
PMID : 32945940
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP17A1 polymorphism c.-362T>C predicts clinical outcome in metastatic castration-resistance prostate cancer patients treated with abiraterone. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Our aim was to investigate the association between the single nucleotide polymorphism (SNP) c.-362T>C in the CYP17A1 gene, and clinical outcome in mCRPC patients treated with abiraterone. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 3 | CONCLUSIONS: These findings suggest an association between CYP17A1 c.-362T>C polymorphism and poorer clinical outcome with abiraterone for mCRPC patients. | abiraterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |