Pub. Date : 2020 Sep 12
PMID : 32932742
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therefore, we created a model of the histamine-H2R-Gs complex based on the structure of the ternary complex of the beta2-adrenoceptor and investigated the conformational stability of this active GPCR conformation. | Histamine | histamine receptor H2 | Homo sapiens |
| 2 | The cMD and GaMD simulations demonstrate that the active conformation is retained on a mus-timescale in the ternary histamine-H2R-Gs complex and in a truncated complex that contains only Gs helix alpha5 instead of the entire G protein. | Histamine | histamine receptor H2 | Homo sapiens |