Protein Name histamine receptor H2
Organism Homo sapiens
Gene ID 3274
Gene Symbol


UniProt P25021 (HRH2_HUMAN), A0A1B0GTK7 (A0A1B0GTK7_HUMAN)
Relationships Total Number of functionally related compound(s) : 248
Total Number of Articles : 530

histamine receptor H2

Gene Summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

  • histamine H2 receptor
  • gastric receptor 1
  • gastric receptor I
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