Pub. Date : 2020
PMID : 32918225
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | While the p53 clan, mostly in the nucleoplasm, responds to a large and still growing number of alterations in cellular homeostasis commonly referred to as stress, the nuclear VDR is transcriptionally activated after binding its naturally occurring biologically active ligand 1,25-dihydroxyvitamin D with high affinity. | 1,25-dihydroxyvitamin D | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 2 | A second level of interaction is characterized by binding of VDR and p53 protein, an observation that may be of relevance for the ability of 1,25-dihydroxyvitamin D to increase the survival of skin cells after UV irradiation. | 1,25-dihydroxyvitamin D | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |