Title : Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.

Pub. Date : 2020 Nov 25

PMID : 32910646






1 Functional Relationships(s)
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1 Increased fructose consumption and its subsequent metabolism have been implicated in metabolic disorders such as non-alcoholic fatty liver disease and steatohepatitis (NAFLD/NASH) and insulin resistance. Fructose insulin Homo sapiens