Title : Histone deacetylase inhibitor valproic acid attenuates high glucose‑induced endoplasmic reticulum stress and apoptosis in NRK‑52E cells.

Pub. Date : 2020 Nov

PMID : 32901855






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 VPA treatment further upregulated GRP78 expression and attenuated the levels of ATF4, CHOP, caspase-12 and p-JNK. Valproic Acid heat shock protein family A (Hsp70) member 5 Rattus norvegicus
2 Mechanistically, VPA increased the total acetylation levels of histone H4 in NRK-52E cells and increased the histone H4 acetylation of the GRP78 promoter region. Valproic Acid heat shock protein family A (Hsp70) member 5 Rattus norvegicus