Pub. Date : 2020 Nov 1
PMID : 32894758
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential effects of voclosporin and tacrolimus on insulin secretion from human islets. | Tacrolimus | insulin | Homo sapiens |
| 2 | TAC, but not VCS, caused a significant impairment of 15 mM glucose-stimulated and 30 mM KCl-stimulated insulin secretion. | Tacrolimus | insulin | Homo sapiens |
| 3 | Clinically relevant doses of TAC, but not VCS, directly inhibit insulin secretion from human islets, likely via transcriptional control of exocytosis machinery. | Tacrolimus | insulin | Homo sapiens |