Title : Vagal-α7nAChR signaling attenuates allergic asthma responses and facilitates asthma tolerance by regulating inflammatory group 2 innate lymphoid cells.

Pub. Date : 2021 Feb

PMID : 32893406






2 Functional Relationships(s)
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1 The vagus nerve innervating the airways releases acetylcholine (ACh) or neuropeptides (i.e. CGRP) via pulmonary C fibres (PCFs), which could regulate ILC2 activity upon binding the alpha7 nicotinic acetylcholine receptor (alpha7nAChR, coded by Chrna7) or neuropeptide receptors. Acetylcholine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 The vagus nerve innervating the airways releases acetylcholine (ACh) or neuropeptides (i.e. CGRP) via pulmonary C fibres (PCFs), which could regulate ILC2 activity upon binding the alpha7 nicotinic acetylcholine receptor (alpha7nAChR, coded by Chrna7) or neuropeptide receptors. Acetylcholine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus