Title : An In Vitro and In Vivo Evaluation of the Effect of Relacorilant on the Activity of Cytochrome P450 Drug Metabolizing Enzymes.

Pub. Date : 2021 Feb

PMID : 32869328






1 Functional Relationships(s)
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1 A clinical study in healthy subjects (n = 27) evaluated the inhibition of CYP3A4, CYP2C8, and CYP2C9 in vivo by administering single doses of probe CYP substrates (midazolam, pioglitazone, and tolbutamide) alone and in combination with relacorilant (350 mg). Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens