Title : Thrombin-activated PAR1 membrane expression is regulated by Rab11a-RCP complex dissociation.

Pub. Date : 2020 Nov

PMID : 32860953






2 Functional Relationships(s)
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1 Hereby we demonstrate that thrombin-induced PAR1 internalization and lysosomal targeting requires the disassembly of the Rab11a/RCP complex, and that this process depends on thrombin-induced intracellular calcium increase and calpain activation. Calcium coagulation factor II, thrombin Homo sapiens
2 Hereby we demonstrate that thrombin-induced PAR1 internalization and lysosomal targeting requires the disassembly of the Rab11a/RCP complex, and that this process depends on thrombin-induced intracellular calcium increase and calpain activation. Calcium coagulation factor II, thrombin Homo sapiens