Title : Prenatal Exposure to Electronic-Cigarette Aerosols Leads to Sex-Dependent Pulmonary Extracellular-Matrix Remodeling and Myogenesis in Offspring Mice.

Pub. Date : 2020 Dec

PMID : 32853043






2 Functional Relationships(s)
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1 Compared with the air-exposed control group, female mice exposed to e-cig aerosols, with or without nicotine, demonstrated increased lung protein abundance of LEF-1 (lymphoid enhancer-binding factor 1), fibronectin, and E-cadherin, whereas altered E-cadherin and PPARgamma (peroxisome proliferator-activated receptor gamma) levels were observed only in males exposed to e-cig aerosols with nicotine. Nicotine lymphoid enhancer binding factor 1 Mus musculus
2 Compared with the air-exposed control group, female mice exposed to e-cig aerosols, with or without nicotine, demonstrated increased lung protein abundance of LEF-1 (lymphoid enhancer-binding factor 1), fibronectin, and E-cadherin, whereas altered E-cadherin and PPARgamma (peroxisome proliferator-activated receptor gamma) levels were observed only in males exposed to e-cig aerosols with nicotine. Nicotine lymphoid enhancer binding factor 1 Mus musculus