Title : Dihydromyricetin Protects Against Gentamicin-Induced Ototoxicity via PGC-1α/SIRT3 Signaling in vitro.

Pub. Date : 2020

PMID : 32850822






3 Functional Relationships(s)
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1 Dihydromyricetin Protects Against Gentamicin-Induced Ototoxicity via PGC-1alpha/SIRT3 Signaling in vitro. dihydromyricetin sirtuin 3 Homo sapiens
2 And the role of PGC-1alpha and SIRT3 in the protective effects of DHM was evaluated by pharmacologic inhibition of these factors using SR-18292 and 3-(1H-1,2,3-triazol-4-yl) pyridine, respectively, which indicated DHM"s protective effect was dependent on activation of the PGC-1alpha/SIRT3 signaling. dihydromyricetin sirtuin 3 Homo sapiens
3 And the role of PGC-1alpha and SIRT3 in the protective effects of DHM was evaluated by pharmacologic inhibition of these factors using SR-18292 and 3-(1H-1,2,3-triazol-4-yl) pyridine, respectively, which indicated DHM"s protective effect was dependent on activation of the PGC-1alpha/SIRT3 signaling. dihydromyricetin sirtuin 3 Homo sapiens