Title : Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy on Ischemic Outcomes After Percutaneous Coronary Intervention: The TAILOR-PCI Randomized Clinical Trial.

Pub. Date : 2020 Aug 25

PMID : 32840598






2 Functional Relationships(s)
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Protein Name
Organism
1 CYP2C19 LOF carriers were prescribed ticagrelor and noncarriers clopidogrel. Ticagrelor cytochrome P450 family 2 subfamily C member 19 Homo sapiens
2 Of 1849 with CYP2C19 LOF variants, 764 of 903 (85%) assigned to genotype-guided therapy received ticagrelor, and 932 of 946 (99%) assigned to conventional therapy received clopidogrel. Ticagrelor cytochrome P450 family 2 subfamily C member 19 Homo sapiens