Title : Evaluation of active Rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis.

Pub. Date : 2020 Oct 2

PMID : 32817335






1 Functional Relationships(s)
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1 These results have profound implications for the study of this key GTPase in cancer, particularly because a large number of cancer cell lines with characteristic mesenchymal features show simultaneous up-regulation of vimentin and high basal Rac1-GTP levels when measured biochemically. Guanosine Triphosphate vimentin Homo sapiens