Title : MDM2 Antagonists Induce a Paradoxical Activation of Erk1/2 through a P53-Dependent Mechanism in Dedifferentiated Liposarcomas: Implications for Combinatorial Strategies.

Pub. Date : 2020 Aug 12

PMID : 32806555






1 Functional Relationships(s)
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1 MDM2 antagonist (RG7388)-resistant IB115 [P4] cells and p53-silenced DDLPS cells were also established to understand the importance of functional p53. RG7388 transformed mouse 3T3 cell double minute 2 Mus musculus