Title : The Effect of Low-Level Laser Therapy and Curcumin on the Expression of LC3, ATG10 and BAX/BCL2 Ratio in PC12 Cells Induced by 6-Hydroxide Dopamine.

Pub. Date : 2020 Summer

PMID : 32802291






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1 The Effect of Low-Level Laser Therapy and Curcumin on the Expression of LC3, ATG10 and BAX/BCL2 Ratio in PC12 Cells Induced by 6-Hydroxide Dopamine. Curcumin BCL2, apoptosis regulator Rattus norvegicus
2 CU+LLLT decreases Bax/Bcl2 ratio which is an indicator of apoptosis and it also rescued a decrease in LC3 and ATG10 expression in comparison with 6-OHDA group. Curcumin BCL2, apoptosis regulator Rattus norvegicus
3 Conclusion: This study shows that the combination of 5 muM CU and LLLT has the best neuroprotective effect on PC12 cells against 6-OHDA by decreasing the BAX/BCL2 ratio. Curcumin BCL2, apoptosis regulator Rattus norvegicus