Title : Regulation of MFN2 by berberine alleviates obesity exacerbated colitis.

Pub. Date : 2020 Oct 15

PMID : 32800336






1 Functional Relationships(s)
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1 In vitro, we stimulated Caco-2 cells with palmitic acid (PA) to replicate the lipotoxicity damage in the intestine, and the results presented that intervention therapy of berberine effectively enhanced the MFN2 expression, inhibited the mRNA levels of inflammatory factors, and reversed the PA induced protein level changes of AMPK and BIP/Grp78. Berberine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens