Title : Dexmedetomidine alleviates non-ventilation associated lung injury via modulating immunology phenotypes of macrophages.

Pub. Date : 2020 Oct 15

PMID : 32798558






1 Functional Relationships(s)
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1 Results from rats demonstrated that treatment with Dex reversed the increased inflammatory cells in lung and the increased levels of TNF-alpha, interleukin-1beta (IL-beta), MCP-1 and chemokine (C-X-C motif) ligand 1 (CXCL1) resulted from non-ventilation; Dex increased the anti-inflammatory cytokine interleukin-10 (IL-10) in BALF from non-ventilated lung. Dexmedetomidine tumor necrosis factor Rattus norvegicus