Pub. Date : 2021 Jan
PMID : 32788470
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway. | Acrylamide | brain derived neurotrophic factor | Homo sapiens |
| 2 | Brain-derived neurotrophic factor (BDNF) can alleviate acrylamide-induced synaptic injury; however, the underlying mechanism remains unclear. | Acrylamide | brain derived neurotrophic factor | Homo sapiens |
| 3 | Brain-derived neurotrophic factor (BDNF) can alleviate acrylamide-induced synaptic injury; however, the underlying mechanism remains unclear. | Acrylamide | brain derived neurotrophic factor | Homo sapiens |
| 4 | Exposure of co-cultured NB-1 cells and Schwann cells to 0-100 mug/mL acrylamide for 48 hours resulted in upregulated expression of synapsin I and BDNF, suggesting that Schwann cells can activate self-protection of neurons. | Acrylamide | brain derived neurotrophic factor | Homo sapiens |
| 5 | Therefore, exogenous BDNF may be an effective treatment strategy for acrylamide-induced nerve injury. | Acrylamide | brain derived neurotrophic factor | Homo sapiens |