Title : Curcumin promotes osteogenic differentiation of periodontal ligament stem cells through the PI3K/AKT/Nrf2 signaling pathway.

Pub. Date : 2020 Jul

PMID : 32774819






3 Functional Relationships(s)
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1 Curcumin promotes osteogenic differentiation of periodontal ligament stem cells through the PI3K/AKT/Nrf2 signaling pathway. Curcumin AKT serine/threonine kinase 1 Homo sapiens
2 The results of western blotting and RT-qPCR revealed that the protein and mRNA levels of ALP, COL1 and RUNX2 were increased by curcumin, while the PI3K/AKT/Nrf2 signaling pathway was activated. Curcumin AKT serine/threonine kinase 1 Homo sapiens
3 Conclusion: Curcumin could promote the osteogenesis of hPDLSCs, and the effect is related to the PI3K/AKT/Nrf2 signaling pathway. Curcumin AKT serine/threonine kinase 1 Homo sapiens