Title : Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice.

Pub. Date : 2020 Oct

PMID : 32764093






2 Functional Relationships(s)
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1 CAF +- HAL are studied on RYR1 single-channel currents and HET myotubes to define molecular mechanisms of gene-by-environment synergism. Halothane ryanodine receptor 1, skeletal muscle Mus musculus
2 Central and peripheral nervous systems mediate adverse responses to HAL in a HET model of MH susceptibility exposed to dietary CAF, a modifiable lifestyle factor that may mitigate risks of acute and chronic diseases associated with RYR1 mutations. Halothane ryanodine receptor 1, skeletal muscle Mus musculus