Title : In Vitro and In Vivo Osteogenesis Induced by Icariin and Bone Morphogenetic Protein-2: A Dynamic Observation.

Pub. Date : 2020

PMID : 32760277






3 Functional Relationships(s)
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1 Specifically, ICA at a concentration of 30 microg/ml had the strongest ability to promote cell proliferation, which is equivalent with the effect of BMP-2 at a concentration of 50 microg/ml. icariin bone morphogenetic protein 2 Homo sapiens
2 Furthermore, Western blot and RT-qPCR analyses showed that treatment with ICA (20-30 microg/ml) had similar increase effect with BMP-2 (50 microg/ml) on the protein and mRNA levels of BMP-2, osteoprotegerin (OPG), and alkaline phosphatase (ALP) mRNAs. icariin bone morphogenetic protein 2 Homo sapiens
3 Furthermore, Western blot and RT-qPCR analyses showed that treatment with ICA (20-30 microg/ml) had similar increase effect with BMP-2 (50 microg/ml) on the protein and mRNA levels of BMP-2, osteoprotegerin (OPG), and alkaline phosphatase (ALP) mRNAs. icariin bone morphogenetic protein 2 Homo sapiens